KPV's Phase II trial lasted 8 weeks
Glutamine enters the cell via the ASCT2 / SLC1A5 amino acid transporter and is converted to glutamate in the mitochondria through a glutaminase-catalyzed deamination reaction (GLS)
Chen, Z., Tian, R., She, Z., Cai, J
But we dont have large-scale human trials showing its safe and effective for dental use
Tendon, ligament, post-surgical, systemic inflammation SC injection
because rigorously controlled human safety data specific to the TB-500 fragment does not exist, its longer-term risk profile, including possible immune reactions, remains unknown Evidence snapshot: Evidence for TB-500 itself is preclinical, drawn mainly from cell-culture and animal studies (a 1999 rat wound-healing study and later rodent cardiac- and tendon-injury models), with a 2026 scoping review describing the musculoskeletal literature on thymosin beta-4 and TB-500 as sparse and largely preclinical